Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 8/20 | 0.33 |
| ▸ | BAD | Q92934 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668070 | 0.93 | MEN1 (0.35) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8485120 | 0.91 | TSHR (0.36) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8480927 | 0.82 | NPSR1 (0.41) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8502237 | 0.80 | NPSR1 (0.38) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8480408 | 0.80 | TMEM97 (0.38) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8675063 | 0.79 | L3MBTL1 (0.42) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8502228 | 0.79 | SCN1A (0.33) | SMN1; SMN2NPSR1HTR2A | |
| SCHEMBL8503698 | 0.78 | SCN1A (0.33) | NPSR1 | |
| SCHEMBL8503795 | 0.77 | OPRK1 (0.31) | TSHRMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8503790 | 0.77 | SCN1A (0.32) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |