Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867183 | 0.98 | VCAM1 (0.41) | VCAM1ALDH1A1HSD17B10TDP1HPGD | |
| SCHEMBL31244570 | 0.98 | VCAM1 (0.41) | VCAM1ALDH1A1HSD17B10TDP1HPGD | |
| SCHEMBL9244819 | 0.83 | TDP1 (0.53) | ALDH1A1HSD17B10TDP1HPGDLMNA | |
| SCHEMBL28565819 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1HPGDLMNA | |
| SCHEMBL11825491 | 0.81 | TDP1 (0.50) | VCAM1ALDH1A1HSD17B10TDP1HPGD | |
| Tetrabuthylammonium SCHEMBL19718090 | 0.81 | VCAM1 (0.43) | VCAM1ALDH1A1LMNATSHR | |
| SCHEMBL31696807 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1HPGDLMNA | |
| SCHEMBL10905318 | 0.80 | SNCA (0.42) | VCAM1ALDH1A1TDP1HPGDLMNA | |
| SCHEMBL867702 | 0.79 | PLCG1 (0.44) | VCAM1ALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL29683547 | 0.79 | PLCG1 (0.44) | VCAM1ALDH1A1HSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2020-11-05 | — | — | US | claimed |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2018-03-01 | — | — | US | claimed |
| US-20160221936-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2016-08-04 | — | — | US | claimed |
| US-9353050-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2016-05-31 | — | — | US | claimed |
| US-8969616-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2015-03-03 | — | — | US | claimed |
| US-20130310600-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2013-11-21 | — | — | US | claimed |
| US-20120078007-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2012-03-29 | — | — | US | claimed |
| US-20100094044-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2010-04-15 | — | — | US | claimed |
| US-7662992-B2 | Process for preparation of isosulfan blue | APICORE, LLC (US) | 2010-02-16 | — | — | US | claimed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | claimed |
| WO-2008140564-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-20 | — | — | WO | claimed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | claimed |
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE US LLC (US) | 2020-11-05 | — | — | US | disclosed |
| US-10752580-B2 | Process for preparation of isosulfan blue | APICORE US LLC (US) | 2020-08-25 | — | — | US | disclosed |
| US-10626086-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2020-04-21 | — | — | US | disclosed |
| US-10590071-B2 | Process for the preparation of isosulfan blue | APICORE US LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-7662992-B2 | Process for preparation of isosulfan blue | APICORE, LLC (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2008140564-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | APICORE, LLC (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094044-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885 |
| US-20200347013-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885 |
| US-10752580-B2 | Process for preparation of isosulfan blue | SI, STS, MPST | VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885 |
| US-10626086-B2 | Process for the preparation of isosulfan blue | SI, STS, MPST | VCAM1 3009/4885ALDH1A1 61/4885HSD17B10 1151/4885 |
| US-20120078007-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885 |
| US-20160221936-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885 |
| US-20080293963-A1 | PROCESS FOR PREPARATION ISOSULFAN BLUE | SI, STS, MPST | VCAM1 3123/4885ALDH1A1 70/4885HSD17B10 1188/4885 |
| US-20130310600-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885 |
| US-20180057454-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, STS, MPST | VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885 |
| US-10590071-B2 | Process for the preparation of isosulfan blue | SI, STS, MPST | VCAM1 3009/4885ALDH1A1 61/4885HSD17B10 1151/4885 |
| US-20080281127-A1 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE | SI, MPST, STS | VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.