SCHEMBL867183

SCHEMBL867183

O=Cc1cc(S(=O)(=O)O)ccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.41
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 3/20 0.40
TDP1 Q9NUW8 4/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 2/20 0.38
NT5E P21589 1/20 0.38
NPBWR1 P48145 1/20 0.37
MCHR1 Q99705 1/20 0.37
ERN1 O75460 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31244570 1.00 VCAM1 (0.41) VCAM1ALDH1A1HSD17B10TDP1HPGD
SCHEMBL867703 0.98 VCAM1 (0.40) VCAM1ALDH1A1HSD17B10TDP1HPGD
SCHEMBL9244819 0.85 TDP1 (0.53) ALDH1A1HSD17B10TDP1HPGDLMNA
SCHEMBL11825491 0.83 TDP1 (0.50) VCAM1ALDH1A1HSD17B10TDP1HPGD
Tetrabuthylammonium SCHEMBL19718090 0.83 VCAM1 (0.43) VCAM1ALDH1A1LMNATSHR
SCHEMBL31696807 0.82 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1HPGDLMNA
SCHEMBL10905318 0.82 SNCA (0.42) VCAM1ALDH1A1TDP1HPGDLMNA
SCHEMBL29683547 0.81 PLCG1 (0.44) VCAM1ALDH1A1HSD17B10TDP1LMNA
SCHEMBL21491267 0.81 LMNA (0.51) VCAM1ALDH1A1TDP1LMNAERN1
SCHEMBL867702 0.81 PLCG1 (0.44) VCAM1ALDH1A1HSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200347013-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE US LLC (US) 2020-11-05 US claimed
US-20180057454-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE US LLC (US) 2018-03-01 US claimed
WO-2017218764-A1 METHOD FOR PREPARATION OF ISOSULFAN BLUE BELOTECA, INC. (US) 2017-12-21 WO claimed
US-20160221936-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE US LLC (US) 2016-08-04 US claimed
US-9353050-B2 Process for preparation of isosulfan blue APICORE US LLC (US) 2016-05-31 US claimed
US-8969616-B2 Process for preparation of isosulfan blue APICORE US LLC (US) 2015-03-03 US claimed
US-20130310600-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE, LLC (US) 2013-11-21 US claimed
US-20120078007-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE, LLC (US) 2012-03-29 US claimed
US-20100094044-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE, LLC (US) 2010-04-15 US claimed
US-7662992-B2 Process for preparation of isosulfan blue APICORE, LLC (US) 2010-02-16 US claimed
US-20080293963-A1 PROCESS FOR PREPARATION ISOSULFAN BLUE APICORE, LLC (US) 2008-11-27 US claimed
WO-2008140564-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE, LLC (US) 2008-11-20 WO claimed
US-20080281127-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE APICORE, LLC (US) 2008-11-13 US claimed
US-20250270168-A1 SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE RISING PHARMA HOLDINGS, INC. (US) 2025-08-28 US disclosed
US-12180142-B1 Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale RISING PHARMA HOLDINGS, INC. (US) 2024-12-31 US disclosed
EP-3408331-B1 FIBRE REACTIVE FORMAZAN DYES, THEIR PREPARATION AND THEIR USE HUNTSMAN ADV MAT SWITZERLAND (CH) 2021-10-20 EP disclosed
US-4024123-A TEXTILES DUSSY PAUL 1977-05-17 US disclosed
US-4014644-A OPTICAL BRIGHTENERS FOR POLYAMIDES AND CELLULOSE CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-4013713-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed
US-4013642-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094044-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, MPST, STS VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885
US-20200347013-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, STS, MPST VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885
US-20250270168-A1 SYNTHESIS PROCESS FOR HIGH PURITY ISOSULFAN BLUE USING FLASH CHROMATOGRAPHY IN COMMERCIAL PLANT SCALE CBS, SLC6A12, RPS4Y1 VCAM1 4020/4885ALDH1A1 1717/4885HSD17B10 1744/4885
US-12180142-B1 Synthesis process for high purity isosulfan blue using flash chromatography in commercial plant scale CBS, SLC6A12, RPS4Y1 VCAM1 4020/4885ALDH1A1 1717/4885HSD17B10 1744/4885
US-20120078007-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, MPST, STS VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885
US-20160221936-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, STS, MPST VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885
US-20080293963-A1 PROCESS FOR PREPARATION ISOSULFAN BLUE SI, STS, MPST VCAM1 3123/4885ALDH1A1 70/4885HSD17B10 1188/4885
US-20130310600-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, MPST, STS VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885
US-20180057454-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, STS, MPST VCAM1 2975/4885ALDH1A1 77/4885HSD17B10 1152/4885
US-20080281127-A1 PROCESS FOR PREPARATION OF ISOSULFAN BLUE SI, MPST, STS VCAM1 2785/4885ALDH1A1 89/4885HSD17B10 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.