Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678382 | 0.85 | TLR7 (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8678423 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8677917 | 0.82 | NLRP3 (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8677024 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8681271 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8678404 | 0.76 | GCGR (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8678115 | 0.76 | TLR7 (0.40) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8676900 | 0.74 | L3MBTL1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8680399 | 0.74 | GCGR (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 | |
| SCHEMBL8679202 | 0.73 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0696588-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| US-5453414-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0663396-A1 | 2-Arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5300477-A | 2-arylpyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| CN-1084165-A | 2-Arylpyrimidines and weeding thereof are used | ROHM & HAAS (US) | 1994-03-23 | — | — | CN | disclosed |
| EP-0579424-A1 | 2-substituted pyrimidines and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |