Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685257 | 0.88 | MAOA (0.39) | ALDH1A1GRM2MAOAMAOBPKM | |
| SCHEMBL8683487 | 0.87 | MAOA (0.38) | ALDH1A1GRM2MAOAMAOBPKM | |
| SCHEMBL8880656 | 0.82 | METAP1 (0.38) | ALDH1A1LMNANPSR1KDM4EMAPT | |
| SCHEMBL8879965 | 0.82 | MAPT (0.46) | SMN1; SMN2ALDH1A1L3MBTL1LMNAKDM4E | |
| SCHEMBL8880066 | 0.81 | HRH1 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL8880563 | 0.81 | GABRG2 (0.38) | SMN1; SMN2ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL8881385 | 0.81 | GABRG2 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL8091069 | 0.80 | TBXAS1 (0.36) | SMN1; SMN2ALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL8097517 | 0.80 | KMT2A (0.43) | ALDH1A1LMNAHSD17B10TRPC5HPGD | |
| SCHEMBL8881176 | 0.80 | CYP19A1 (0.43) | SMN1; SMN2ALDH1A1NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789406-A | Indeno 1,2-E!pyrazine-4-ones, their preparation and the medicaments containing them | RHONE-POULENC RORER S.A. (FR) | 1998-08-04 | — | — | US | disclosed |