Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437147 | 0.92 | HPGD (0.45) | POLBALDH1A1MAPTUSP2HPGD | |
| SCHEMBL7435252 | 0.89 | ALDH1A1 (0.45) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7441569 | 0.89 | POLB (0.41) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8887573 | 0.88 | MEN1 (0.43) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8683165 | 0.88 | MEN1 (0.43) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7343248 | 0.87 | POLB (0.45) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7343264 | 0.87 | POLB (0.45) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7301739 | 0.84 | ALDH1A1 (0.43) | POLBKMT2AALDH1A1MAPTUSP2 | |
| SCHEMBL7435127 | 0.83 | PSMB1 (0.40) | POLBALDH1A1PSMB1PSMB5PSMB2 | |
| SCHEMBL7312209 | 0.83 | ALDH1A1 (0.36) | POLBMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |