Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684062 | 0.86 | GAA (0.39) | GPR119SMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL8671973 | 0.84 | NR1H2 (0.35) | GPR119MMP13 | |
| SCHEMBL8666972 | 0.79 | ACE (0.41) | GPR119SMN1; SMN2MAPT | |
| SCHEMBL8671356 | 0.75 | SFRP1 (0.41) | LMNAKDM4ETSHR | |
| SCHEMBL8636376 | 0.74 | NPC1 (0.39) | SMN1; SMN2LMNAKDM4ETSHRMAPT | |
| SCHEMBL8683958 | 0.74 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL8668725 | 0.73 | MEN1 (0.34) | GPR119ALDH1A1USP30GAAMMP13 | |
| SCHEMBL8666222 | 0.70 | SIGMAR1 (0.40) | ALDH1A1TSHRPOLB | |
| SCHEMBL8671382 | 0.69 | UCHL1 (0.35) | GPR119USP30 | |
| Hydrochloric Acid SCHEMBL8683994 | 0.68 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1LMNAUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |