Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671356 | 0.89 | SFRP1 (0.41) | RORCKMT2AMEN1 | |
| SCHEMBL8668725 | 0.88 | MEN1 (0.34) | NR1H2RORCHSD11B1FFAR2KMT2A | |
| SCHEMBL8670608 | 0.85 | SIGMAR1 (0.38) | RORCKMT2AMMP13 | |
| SCHEMBL8683768 | 0.84 | GPR119 (0.36) | GPR119MMP13 | |
| SCHEMBL8666972 | 0.83 | ACE (0.41) | RORCFFAR2KMT2AMEN1GPR119 | |
| SCHEMBL8666883 | 0.80 | AGTR2 (0.34) | FFAR2KMT2A | |
| SCHEMBL8670326 | 0.80 | AGTR2 (0.34) | FFAR2KMT2A | |
| SCHEMBL8870698 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3KMT2AMEN1GPR119 | |
| SCHEMBL8870707 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3KMT2AMEN1GPR119 | |
| SCHEMBL8672023 | 0.79 | LMNA (0.33) | NR1H2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |