Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712827 | 0.93 | LTA4H (0.46) | LTA4HHRH1SLC6A1 | |
| SCHEMBL8690299 | 0.88 | LTA4H (0.45) | LTA4HHTR2AHRH1HTR2BHTR2C | |
| SCHEMBL8716401 | 0.86 | LTA4H (0.46) | LTA4HALDH1A1KMT2AS1PR5SLC6A1 | |
| SCHEMBL8690225 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8712871 | 0.81 | LTA4H (0.57) | LTA4HSLC6A1 | |
| SCHEMBL8718182 | 0.80 | SLC6A1 (0.59) | SLC6A1 | |
| SCHEMBL8718270 | 0.74 | SLC6A1 (0.43) | SLC6A1 | |
| SCHEMBL9084665 | 0.74 | SLC6A1 (0.67) | SLC6A1 | |
| SCHEMBL8718619 | 0.74 | LTA4H (0.52) | LTA4HSLC6A1 | |
| Hydrochloric Acid SCHEMBL9084393 | 0.73 | SLC6A1 (0.66) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | claimed |
| US-5721260-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACID OR ESTER; ANALGESICS, ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-02-24 | — | — | US | claimed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | disclosed |
| US-5721260-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACID OR ESTER; ANALGESICS, ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-02-24 | — | — | US | disclosed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |