Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712827 | 0.86 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8685369 | 0.86 | LTA4H (0.46) | LTA4HSLC6A1S1PR5ALDH1A1KMT2A | |
| SCHEMBL8690225 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8690299 | 0.85 | LTA4H (0.45) | LTA4HSLC6A1S1PR5KDM4EALDH1A1 | |
| SCHEMBL8712871 | 0.75 | LTA4H (0.57) | LTA4HSLC6A1 | |
| SCHEMBL6628169 | 0.72 | CCR3 (0.59) | LTA4H | |
| SCHEMBL6630519 | 0.72 | CCR3 (0.59) | LTA4H | |
| SCHEMBL8635915 | 0.71 | LTA4H (0.83) | LTA4H | |
| SCHEMBL8716399 | 0.70 | LTA4H (0.43) | LTA4HS1PR5KDM4EALDH1A1MEN1 | |
| SCHEMBL9084665 | 0.70 | SLC6A1 (0.67) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |