Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716401 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8685369 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8712827 | 0.85 | LTA4H (0.46) | LTA4HSLC6A1 | |
| SCHEMBL8690299 | 0.84 | LTA4H (0.45) | LTA4HSLC6A1CHRM2CHRM1CHRM3 | |
| SCHEMBL8715371 | 0.80 | SLC6A1 (0.62) | SLC6A1 | |
| SCHEMBL7471275 | 0.74 | SLC6A1 (0.55) | SLC6A1 | |
| SCHEMBL8712871 | 0.74 | LTA4H (0.57) | LTA4HSLC6A1 | |
| SCHEMBL8934806 | 0.72 | SLC6A1 (0.53) | SLC6A1 | |
| Acetic Acid SCHEMBL7473986 | 0.72 | SLC6A1 (0.53) | SLC6A1 | |
| SCHEMBL6628169 | 0.72 | CCR3 (0.59) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | claimed |
| US-5721260-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACID OR ESTER; ANALGESICS, ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-02-24 | — | — | US | claimed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |
| EP-0825981-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-03-04 | — | — | EP | disclosed |
| US-5721260-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACID OR ESTER; ANALGESICS, ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-02-24 | — | — | US | disclosed |
| WO-1996031468-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |