Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686390 | 0.80 | AKR1B1 (0.41) | CGASHPGDCISD1AKR1B1MAOA | |
| SCHEMBL8686691 | 0.75 | AKR1B1 (0.43) | CGASHPGDCISD1AKR1B1MAOA | |
| SCHEMBL8689993 | 0.69 | NLRP3 (0.49) | CGASAKR1B1PTPN1 | |
| SCHEMBL8812630 | 0.67 | HPGD (0.58) | HPGDCISD1AKR1B1 | |
| SCHEMBL8686947 | 0.67 | MAPT (0.37) | — | |
| SCHEMBL8688100 | 0.66 | ESRRA (0.44) | CGASAKR1B1PTPN1 | |
| SCHEMBL4890278 | 0.65 | PKM (0.55) | HPGD | |
| Bromide SCHEMBL7443970 | 0.64 | PKM (0.53) | HPGD | |
| SCHEMBL8686941 | 0.64 | CYP19A1 (0.33) | HPGD | |
| SCHEMBL8687687 | 0.64 | HPGD (0.42) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |