Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689826 | 0.88 | ACLY (0.48) | KDM4EHSD17B10EGFRPTGDR2MAPT | |
| SCHEMBL9238450 | 0.83 | EGFR (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9244182 | 0.81 | EGFR (0.44) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22022202 | 0.78 | PLA2G2A (0.52) | KDM4EALDH1A1HPGDHSD17B10EGFR | |
| SCHEMBL21478268 | 0.76 | PABPC1 (0.46) | KDM4EALDH1A1HPGDHSD17B10EGFR | |
| SCHEMBL24482986 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10EGFR | |
| SCHEMBL11613647 | 0.75 | EGFR (0.45) | KDM4EALDH1A1HPGDEGFRPTGDR2 | |
| SCHEMBL5234885 | 0.71 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HPGDHSD17B10EGFR | |
| SCHEMBL11532944 | 0.71 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22003908 | 0.70 | ACLY (0.78) | PTGDR2MAPK8MAPTMAPK9ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852046-A | Benzo-fused heterocyclic compounds having a 5-membered ring processes for their preparation their use as medicaments their use as diagnostic agents and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |