Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812017 | 0.85 | BIRC5 (0.43) | HRH3KCNH2ALDH1A1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL3817536 | 0.84 | BIRC5 (0.43) | KCNH2ALDH1A1CYP1A2KMT2ASIGMAR1 | |
| SCHEMBL2097540 | 0.82 | NPC1 (0.41) | RXRBRXRARXRGALDH1A1MAPT | |
| SCHEMBL15975066 | 0.79 | SIGMAR1 (0.45) | SLC6A4HRH3RXRBRXRARXRG | |
| SCHEMBL5905888 | 0.73 | HRH3 (0.64) | HRH3 | |
| SCHEMBL3811959 | 0.73 | ALOX15 (0.55) | RXRBRXRARXRGALDH1A1 | |
| SCHEMBL3811595 | 0.72 | TRPM8 (0.46) | SLC6A4RXRBRXRARXRGMEN1 | |
| SCHEMBL3811751 | 0.72 | SIGMAR1 (0.57) | HRH3ALDH1A1CYP1A2SIGMAR1 | |
| SCHEMBL9720050 | 0.72 | TSHR (0.46) | RXRBRXRARXRGALDH1A1CYP1A2 | |
| SCHEMBL3817676 | 0.72 | TAAR1 (0.51) | SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719150-A | ALZHEIMER'S DISEASE | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |