Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693790 | 0.92 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL8698701 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPK1KDRMTOR | |
| SCHEMBL8696794 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL8698799 | 0.84 | MAPT (0.50) | ALDH1A1LMNAMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL8694014 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1KDRMTOR | |
| SCHEMBL8693505 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL8693996 | 0.83 | AGTR1 (0.47) | ALDH1A1LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL8696204 | 0.82 | FAAH (0.48) | ALDH1A1LMNAKDM4ENPC1KMT2A | |
| SCHEMBL8698769 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPK1KDM4ENPC1 | |
| SCHEMBL14542033 | 0.81 | PDE4B (0.49) | ALDH1A1LMNAMAPK1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |