Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696208 | 0.89 | POLB (0.38) | NPSR1MLYCDALDH1A1SMN1; SMN2HDAC3 | |
| SCHEMBL8695688 | 0.89 | NOX1 (0.36) | NPSR1MLYCDALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL8696072 | 0.82 | ALDH1A1 (0.47) | ALDH1A1RECQLL3MBTL1LMNALTB4R2 | |
| SCHEMBL8696885 | 0.81 | MLYCD (0.45) | MLYCDALDH1A1MAPTLMNAHTT | |
| SCHEMBL8790977 | 0.79 | HDAC3 (0.37) | NPSR1ALDH1A1RECQLSMN1; SMN2HDAC3 | |
| SCHEMBL8698422 | 0.74 | MLYCD (0.35) | MLYCDALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8699518 | 0.73 | ALDH1A1 (0.44) | MLYCDALDH1A1RECQLSMN1; SMN2HDAC1 | |
| SCHEMBL8701009 | 0.72 | ALOX5 (0.46) | NPSR1MLYCDALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL12051678 | 0.71 | ALDH1A1 (0.68) | NPSR1ALDH1A1RECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL8696994 | 0.71 | ALDH1A1 (0.46) | ALDH1A1RECQLHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |