Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702736 | 0.92 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8697348 | 0.88 | — | — | |
| SCHEMBL8696669 | 0.86 | — | — | |
| SCHEMBL7999278 | 0.73 | LTA4H (0.39) | KDM4EGAAALDH1A1TP53MEN1 | |
| SCHEMBL7758845 | 0.65 | LDHA (0.48) | — | |
| SCHEMBL8008735 | 0.63 | KCNA5 (0.37) | ALDH1A1 | |
| SCHEMBL8416462 | 0.62 | MGAT2 (0.35) | — | |
| SCHEMBL8008687 | 0.61 | LDHA (0.41) | — | |
| SCHEMBL8010782 | 0.59 | LDHA (0.38) | GAA | |
| SCHEMBL7074874 | 0.59 | KDM4E (0.35) | KDM4EGAAALDH1A1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834506-A | TREATMENT OF HIV, AIDS; ANTIVIRAL ACTIVITY IMPROVED BY JUDICIOUS PLACEMENT OF POLAR SUBSTITUENTS | WARNER-LAMBERT COMPANY (US) | 1998-11-10 | — | — | US | claimed |
| US-5834506-A | TREATMENT OF HIV, AIDS; ANTIVIRAL ACTIVITY IMPROVED BY JUDICIOUS PLACEMENT OF POLAR SUBSTITUENTS | WARNER-LAMBERT COMPANY (US) | 1998-11-10 | — | — | US | disclosed |