Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594029 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL2238017 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL11503418 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL1705097 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL6308809 | 0.80 | PKM (0.47) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL28554321 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL26135537 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| Chloroacetic Acid SCHEMBL8697102 | 0.77 | ABAT (0.47) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL8840792 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL658053 | 0.77 | LMNA (0.54) | ALDH1A1MAPTRAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767290-A | PROTECTION OF AMINE BY A TOCOPHERYL RADICAL; MILD CONDITIONS FOR DEPROTECTING; SYNTHESIS OF OLIGOPEPTIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| US-5684132-A | DEHYDROHALOGENATION OR DESULFATION AND AMINATION TO ADD TOCOPHEROL GROUPS | BASF AKTIENGSELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |