Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 7/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698458 | 0.79 | ENPP2 (0.38) | ENPP2NR3C1GNRHRSLC6A2SLC6A4 | |
| SCHEMBL8689640 | 0.69 | MAOA (0.36) | NR3C1SLC6A2SLC6A4SLC6A3CCNC | |
| SCHEMBL8697815 | 0.67 | PTGS2 (0.36) | NR3C1SLC6A2SLC6A4SLC6A3CCNC | |
| SCHEMBL8695280 | 0.64 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2301833 | 0.59 | SLC6A2 (0.54) | ENPP2NR3C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27608010 | 0.58 | ENPP2 (0.53) | ENPP2SLC6A2SLC6A4SLC6A3HDAC1 | |
| SCHEMBL27742085 | 0.57 | SLC6A2 (0.46) | ENPP2F10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10830196 | 0.56 | ENPP2 (0.46) | ENPP2F2HDAC1HDAC8 | |
| SCHEMBL28154516 | 0.56 | MMP8 (0.52) | SLC6A2SLC6A3 | |
| SCHEMBL188098 | 0.56 | ENPP2 (0.60) | ENPP2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |