Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698200 | 0.81 | SIGMAR1 (0.47) | PKML3MBTL1MIFALDH1A1PDE10A | |
| SCHEMBL8704016 | 0.74 | TAAR1 (0.41) | MIFALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL8698519 | 0.71 | PSMB8 (0.45) | PKML3MBTL1ALDH1A1HSD17B10HRH3 | |
| SCHEMBL8698563 | 0.70 | BRD4 (0.38) | PKMMIFALDH1A1NPSR1TSHR | |
| SCHEMBL5252911 | 0.67 | ALDH1A1 (0.47) | L3MBTL1MIFALDH1A1NPSR1NPC1 | |
| SCHEMBL15081590 | 0.67 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1HRH3NPC1RAB9A | |
| SCHEMBL2750729 | 0.65 | L3MBTL1 (0.42) | PKML3MBTL1ALDH1A1PDE10ANPC1 | |
| SCHEMBL2750291 | 0.65 | L3MBTL1 (0.56) | L3MBTL1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30978218 | 0.65 | L3MBTL1 (0.56) | L3MBTL1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17156193 | 0.64 | GABRA5 (0.43) | PKML3MBTL1MIFALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |