Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SHH | Q15465 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704331 | 0.85 | SLC6A3 (0.50) | MAPTNPSR1SDHBSLC6A3SLC6A4 | |
| SCHEMBL8446254 | 0.81 | — | — | |
| SCHEMBL8699887 | 0.80 | NR4A2 (0.50) | ALDH1A1HTR2AHTR2CKDM4E | |
| SCHEMBL8701058 | 0.79 | MAPT (0.40) | MAPTNPSR1ALDH1A1TSHRCYP46A1 | |
| SCHEMBL8699627 | 0.78 | CYP46A1 (0.51) | MAPTNPSR1ALDH1A1TSHRSLC6A3 | |
| SCHEMBL8706150 | 0.76 | ALPL (0.40) | MAPTNPSR1ALDH1A1TSHRPDE4A | |
| SCHEMBL8610220 | 0.74 | SLC9A1 (0.51) | MAPTNPSR1ALDH1A1TSHRSLC6A3 | |
| SCHEMBL8575467 | 0.74 | MAPT (0.53) | MAPTNPSR1ALDH1A1TSHRCA1 | |
| SCHEMBL8706096 | 0.73 | ACLY (0.46) | MAPTNPSR1ALDH1A1TSHRCA1 | |
| SCHEMBL28603205 | 0.73 | SLC6A3 (0.53) | MAPTNPSR1SDHBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |