Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701409 | 0.86 | MAPT (0.40) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL7835065 | 0.84 | SLC9A1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL7836893 | 0.84 | SLC9A1 (0.47) | — | |
| SCHEMBL9177701 | 0.83 | SUV39H2 (0.42) | GPR119 | |
| SCHEMBL9177710 | 0.77 | STS (0.38) | EEDKDM4EALDH1A1HPGDGPR119 | |
| SCHEMBL8701738 | 0.75 | SLC9A1 (0.49) | EEDKDM4EGAAMEN1KMT2A | |
| SCHEMBL8584065 | 0.74 | GAA (0.41) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL8700566 | 0.73 | KDM4E (0.55) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL8705825 | 0.73 | KDM4E (0.48) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8704148 | 0.72 | EED (0.40) | EEDKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |