Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.58 |
| ▸ | RARA | P10276 | 6/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 16/20 | 0.47 |
| ▸ | RXRB | P28702 | 12/20 | 0.47 |
| ▸ | RXRG | P48443 | 11/20 | 0.47 |
| ▸ | RARG | P13631 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293243 | 0.81 | RARA (0.48) | RARBRARAHNF4ARXRARXRB | |
| SCHEMBL3341864 | 0.78 | RARB (0.52) | RARBRARAHNF4ARXRARXRB | |
| SCHEMBL5359740 | 0.77 | RXRA (0.71) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8708359 | 0.75 | RARA (0.44) | RARBRARAHNF4ARXRA | |
| SCHEMBL12715251 | 0.73 | RARA (0.43) | RARBRARAHNF4ARXRARARG | |
| SCHEMBL10694294 | 0.72 | RARB (0.58) | RARBRARAHNF4ARXRARXRB | |
| SCHEMBL9145602 | 0.72 | RARB (0.47) | RARBRARAHNF4ARXRARXRB | |
| SCHEMBL28646163 | 0.69 | RXRA (0.59) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8461952 | 0.69 | RARA (0.67) | RARBRARARXRARARGMEN1 | |
| SCHEMBL9850270 | 0.69 | RXRA (0.55) | RARBRARAHNF4ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007716-A2 | HETEROAROTINOIDS-ANTICANCER AGENTS WITH RECEPTOR SPECIFICITY AND TGASE ACTIVITY | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 1998-02-26 | — | — | WO | disclosed |