Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293243 | 0.86 | RARA (0.48) | RARARARBRXRAHNF4AL3MBTL1 | |
| SCHEMBL12715251 | 0.78 | RARA (0.43) | RARARARBRXRAHNF4A | |
| SCHEMBL8293242 | 0.76 | RARA (0.48) | RARARARBHNF4APOLBPTGS1 | |
| SCHEMBL5023386 | 0.76 | RARA (0.41) | RARARARBHNF4A | |
| SCHEMBL8700476 | 0.75 | RARB (0.58) | RARARARBRXRAHNF4A | |
| SCHEMBL8699677 | 0.75 | RARA (0.44) | RARARARB | |
| SCHEMBL9143502 | 0.75 | GABRA1 (0.38) | RARARARBHNF4APTGS1PTGS2 | |
| SCHEMBL3170254 | 0.74 | RXRA (0.44) | RARARARBRXRA | |
| SCHEMBL7709686 | 0.73 | RARA (0.43) | RARARARB | |
| SCHEMBL17771779 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998007716-A2 | HETEROAROTINOIDS-ANTICANCER AGENTS WITH RECEPTOR SPECIFICITY AND TGASE ACTIVITY | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 1998-02-26 | — | — | WO | disclosed |