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Glutamine

Glutamine

SCHEMBL8700598

CSCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NCC(=O)O.NCC(=O)O.NCC(=O)OC(=O)CN.O=C(O)[C@@H]1CCCN1.O=C(OC1CCN[C@@H]1C(=O)O)[C@@H]1CCCN1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL8704393 1.00 MEN1 (0.33) MEN1KMT2A
Proline SCHEMBL6690171 0.81 MEN1 (0.32) MEN1KMT2A
Glutamic Acid SCHEMBL6740018 0.79 MEN1 (0.41) MEN1KMT2A
Racemethionine SCHEMBL23924542 0.79 MEN1 (0.43) MEN1KMT2A
Methionine SCHEMBL4402781 0.79 MEN1 (0.43) MEN1KMT2A
Methionine SCHEMBL3091904 0.79 MEN1 (0.43) MEN1KMT2A
Threonine SCHEMBL6689276 0.78 — —
Glutamine SCHEMBL8704396 0.78 KMT2A (0.35) MEN1KMT2A
Glutamine SCHEMBL8700601 0.78 KMT2A (0.35) MEN1KMT2A
Glutamine SCHEMBL4298256 0.77 ALOX15 (0.50) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849323-A Collagen mimetic and method of treating rheumatoid arthritis using same Braswell, A. Glenn (US) 1998-12-15 — — US claimed
US-5849323-A Collagen mimetic and method of treating rheumatoid arthritis using same Braswell, A. Glenn (US) 1998-12-15 — — US disclosed
US-5849323-A Collagen mimetic and method of treating rheumatoid arthritis using same Braswell, A. Glenn (US) 1998-12-15 — — US disclosed