Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634178 | 0.72 | CA12 (0.43) | LMNAKDM4ECYP1A2ALDH1A1HPGD | |
| SCHEMBL8700660 | 0.67 | ACSS2 (0.48) | LMNAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8697702 | 0.67 | ALDH1A1 (0.37) | LMNAKDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23195611 | 0.66 | CA12 (0.44) | LMNAKDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10895643 | 0.64 | CA12 (0.60) | LMNACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23196121 | 0.64 | CA12 (0.45) | LMNAKDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11231488 | 0.64 | CA12 (0.47) | LMNAKDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1264358 | 0.64 | LMNA (0.54) | LMNAKDM4ECYP1A2ALDH1A1HPGD | |
| SCHEMBL5924185 | 0.63 | CA12 (0.55) | LMNACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7075007 | 0.63 | ADORA3 (0.43) | LMNAKDM4ECYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018768-A1 | HERBICIDAL 3-(BICYCLIC NITROGEN-CONTAINING HETEROCYCLE)-SUBSTITUTED-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1998-05-07 | — | — | WO | disclosed |