Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700585 | 0.81 | PDE4B (0.41) | ALDH1A1SMN1; SMN2MRGPRX1MAPTKMT2A | |
| SCHEMBL8705533 | 0.79 | AOC2 (0.51) | ALDH1A1MAPTTDP1KMT2AL3MBTL1 | |
| SCHEMBL8701429 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MRGPRX1HCRTR1HCRTR2 | |
| SCHEMBL8705142 | 0.77 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MRGPRX1MAPTKMT2A | |
| Guanidine SCHEMBL8701424 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MRGPRX1HCRTR1HCRTR2 | |
| SCHEMBL8704992 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL8707033 | 0.73 | AOC2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8703318 | 0.72 | AOC2 (0.33) | TDP1L3MBTL1F10 | |
| SCHEMBL7830164 | 0.72 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL7815979 | 0.72 | SLC9A1 (0.47) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |