Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705961 | 0.86 | KMT2A (0.44) | LMNAKMT2APKMKDM4EALOX15 | |
| SCHEMBL8705630 | 0.86 | LMNA (0.42) | LMNAKMT2AHTT | |
| SCHEMBL8709426 | 0.84 | KMT2A (0.43) | LMNAKMT2APKMKDM4EALOX15 | |
| SCHEMBL8710396 | 0.83 | LMNA (0.42) | LMNAKMT2ATSHRHTTMEN1 | |
| SCHEMBL8705275 | 0.81 | KMT2A (0.47) | LMNAKMT2APKMKDM4EALOX15 | |
| SCHEMBL8707955 | 0.78 | CCR1 (0.44) | LMNAKMT2AMEN1 | |
| SCHEMBL8703449 | 0.75 | LMNA (0.37) | LMNAKMT2AHTTMEN1MITF | |
| Hydrochloric Acid SCHEMBL8705245 | 0.72 | HTR7 (0.51) | TSHR | |
| SCHEMBL8710606 | 0.72 | LMNA (0.35) | LMNAKMT2ATSHRMEN1 | |
| SCHEMBL8709417 | 0.70 | ALDH1A1 (0.39) | LMNAKMT2AHTTPARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |