Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705630 | 0.73 | LMNA (0.42) | LMNAKMT2AHTT | |
| SCHEMBL8711235 | 0.72 | KMT2A (0.37) | LMNAHTR1AADRA1AKMT2AMEN1 | |
| SCHEMBL8710396 | 0.70 | LMNA (0.42) | LMNAKMT2AMEN1HTT | |
| SCHEMBL8707955 | 0.66 | CCR1 (0.44) | LMNAKMT2AMEN1 | |
| SCHEMBL8705961 | 0.64 | KMT2A (0.44) | LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8705245 | 0.63 | HTR7 (0.51) | HTR1AADRA1A | |
| SCHEMBL8704259 | 0.63 | KDM5A (0.42) | KMT2AMEN1KIF11 | |
| SCHEMBL6070188 | 0.63 | ALDH1A1 (0.61) | HTR1AADRA1AKMT2AMEN1KIF11 | |
| SCHEMBL8709426 | 0.62 | KMT2A (0.43) | LMNAKMT2AHTT | |
| SCHEMBL8710606 | 0.61 | LMNA (0.35) | LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998002432-A1 | BICYCLIC COMPOUNDS FOR CONTROLLING MICTURITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-22 | — | — | WO | disclosed |