SCHEMBL8707994

SCHEMBL8707994

Cc1c(Cl)c(O)nc2cc[c]cc12

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8707262 0.81
SCHEMBL8703296 0.71 MAPT (0.44) MAPT
SCHEMBL10674984 0.71
SCHEMBL8702455 0.70 CYP1A2 (0.35) MAPT
SCHEMBL6986503 0.70 ESR1 (0.36) MAOAMAOBMAPT
SCHEMBL6714495 0.69
SCHEMBL8486872 0.68 HSD17B10 (0.39) MAOAMAPT
SCHEMBL8703308 0.67 ESR1 (0.40)
SCHEMBL10623525 0.66 MYC (0.31)
SCHEMBL28509099 0.66 KDM4E (0.35) MAOAMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed