Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20476372 | 0.85 | KDM4E (0.32) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL6986503 | 0.81 | ESR1 (0.36) | LMNAMAOAMAOBESRRBESR1 | |
| SCHEMBL693400 | 0.79 | NT5E (0.55) | KDM4ENT5EMAPT | |
| SCHEMBL397020 | 0.71 | MAOA (0.54) | KDM4ECYP3A4CYP2C19MAOAMAOB | |
| SCHEMBL29420516 | 0.71 | MAOA (0.54) | KDM4ECYP3A4CYP2C19MAOAMAOB | |
| SCHEMBL6995818 | 0.71 | ALDH1A1 (0.40) | KDM4ELMNAMAPT | |
| SCHEMBL4455983 | 0.71 | AXL (0.37) | KDM4ECYP2C19MAPT | |
| SCHEMBL15516443 | 0.70 | KDM4E (0.47) | KDM4ECYP3A4CYP2C19HIF1ALMNA | |
| SCHEMBL865202 | 0.69 | CRHBP (0.32) | — | |
| SCHEMBL29799170 | 0.69 | LMNA (0.46) | KDM4ECYP3A4CYP2C19HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-112204010-A | Heterocyclic derivatives and use thereof | C&C新药研究所 | 2021-01-08 | — | — | CN | disclosed |