Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.34 |
| ▸ | HTR2A | P28223 | 17/20 | 0.34 |
| ▸ | DRD3 | P35462 | 17/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549413 | 0.79 | ALDH1A1 (0.40) | DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL8710593 | 0.77 | CHRM4 (0.42) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8710324 | 0.72 | ALDH1A1 (0.43) | DRD2HTR2ADRD3 | |
| SCHEMBL8703860 | 0.71 | DRD2 (0.37) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8704044 | 0.71 | UBE2M (0.42) | DRD2SLC6A4 | |
| SCHEMBL8548758 | 0.69 | DRD2 (0.40) | DRD2HTR2ADRD3 | |
| SCHEMBL8715170 | 0.69 | DRD2 (0.43) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8704542 | 0.68 | ALDH1A1 (0.53) | DRD2HTR2ADRD3SLC6A4 | |
| SCHEMBL8548755 | 0.67 | CA2 (0.43) | DRD2HTR2ADRD3 | |
| SCHEMBL8549417 | 0.67 | DRD2 (0.39) | DRD2HTR2ADRD3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |