Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | BHMT | Q93088 | 1/20 | 0.40 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norleucine SCHEMBL4068644 | 0.89 | SLC1A2 (0.53) | SLC1A2SLC1A1SLC1A3DDAH1NOS3 | |
| Norleucine SCHEMBL4068645 | 0.89 | SLC1A2 (0.53) | SLC1A2SLC1A1SLC1A3DDAH1NOS3 | |
| Norleucine SCHEMBL12485005 | 0.86 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3DDAH1NOS3 | |
| Norleucine SCHEMBL12485007 | 0.86 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3DDAH1NOS3 | |
| SCHEMBL108559 | 0.84 | MARS1 (0.44) | — | |
| SCHEMBL108560 | 0.84 | MARS1 (0.44) | — | |
| SCHEMBL3089957 | 0.84 | MARS1 (0.44) | — | |
| Ornithine SCHEMBL15322979 | 0.83 | GSR (0.45) | SLC1A2SLC1A1SLC1A3NOD1DDAH1 | |
| SCHEMBL4068647 | 0.83 | DPP7 (0.41) | SLC1A2SLC1A1SLC1A3NOD1CA1 | |
| Leucine SCHEMBL15323405 | 0.82 | SLC7A5 (0.53) | SLC1A2SLC1A1SLC1A3NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786322-A | DIAGNOSTIC DETERMINING A SITE OF INFLAMMATION IN PATIENT | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-07-28 | — | — | US | disclosed |
| US-5643873-A | ANTIINFLAMMATORY | AFFYMAX TECHNOLOGIES N.V. (AN) | 1997-07-01 | — | — | US | disclosed |