Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359535 | 0.86 | FGFR1 (0.36) | AGTR2FGFR1SRCBTK | |
| SCHEMBL8357506 | 0.84 | FGFR1 (0.36) | AGTR2FGFR1SRCBTK | |
| SCHEMBL8421706 | 0.84 | FGFR1 (0.37) | FGFR1SRC | |
| SCHEMBL8505059 | 0.79 | AGTR2 (0.45) | AGTR2AGTR1LTB4R2 | |
| SCHEMBL8419025 | 0.77 | FGFR1 (0.36) | FGFR1SRC | |
| SCHEMBL8504867 | 0.77 | AGTR2 (0.43) | AGTR2AGTR1LTB4R2 | |
| SCHEMBL8359335 | 0.77 | PLA2G2A (0.36) | AGTR2AGTR1FGFR1SRC | |
| SCHEMBL8361978 | 0.77 | PLA2G2A (0.36) | AGTR2AGTR1FGFR1SRC | |
| SCHEMBL8587857 | 0.77 | FGFR1 (0.36) | FGFR1SRC | |
| SCHEMBL8635495 | 0.77 | FGFR1 (0.42) | FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750551-A | ANGIOTENSIN INHIBITORS, BENZIMIDAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-12 | — | — | US | claimed |