Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713886 | 0.95 | HTR1A (0.34) | DRD2HTR1ADRD4MAPK1KCNH2 | |
| SCHEMBL8713586 | 0.93 | KDM1A (0.35) | DRD2HTR1ADRD4NPY1RDRD3 | |
| SCHEMBL8717917 | 0.88 | KDM1A (0.34) | DRD2HTR1ADRD4ALDH1A1TSHR | |
| SCHEMBL8712463 | 0.84 | GPR119 (0.43) | KDM4E | |
| SCHEMBL8713635 | 0.81 | ALDH1A1 (0.33) | DRD2HTR1ANPY1RKCNH2ALDH1A1 | |
| SCHEMBL7871606 | 0.80 | GPR119 (0.45) | ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8716168 | 0.79 | NPY1R (0.40) | NPY1R | |
| SCHEMBL7863439 | 0.77 | DRD2 (0.34) | DRD2HTR1ADRD4KCNH2DRD3 | |
| SCHEMBL7872441 | 0.77 | DRD2 (0.33) | DRD2HTR1ADRD4KCNH2DRD3 | |
| SCHEMBL8718329 | 0.77 | ALDH1A1 (0.33) | DRD2HTR1AKCNH2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |