Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.58 |
| ▸ | MMP2 | P08253 | 4/20 | 0.58 |
| ▸ | MMP3 | P08254 | 4/20 | 0.58 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | PDE4A | P27815 | 4/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559633 | 0.78 | MMP1 (0.70) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL8014627 | 0.77 | MMP2 (0.78) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL4796914 | 0.77 | NPC1 (0.58) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL7417705 | 0.76 | MMP1 (0.48) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL6929276 | 0.75 | MMP1 (0.70) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL7207784 | 0.75 | MMP2 (0.54) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL16540402 | 0.73 | MMP13 (0.55) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL28548434 | 0.71 | NPC1 (0.54) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL4493891 | 0.71 | ACP3 (0.57) | NPC1ALDH1A1RAB9AMAPTEPHX1 | |
| SCHEMBL7352846 | 0.71 | MMP13 (0.60) | MMP1MMP2MMP3MMP13PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847153-A | β-sulfonyl hydroxamic acids | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |