Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713251 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTLMNAKDM4ETDP1 | |
| SCHEMBL8715549 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTLMNAKDM4ETDP1 | |
| SCHEMBL8715547 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTLMNAKDM4ETDP1 | |
| SCHEMBL8714130 | 0.84 | LDHA (0.48) | LMNAKDM4EPPARAPPARDALDH1A1 | |
| SCHEMBL8714129 | 0.84 | LDHA (0.48) | LMNAKDM4EPPARAPPARDALDH1A1 | |
| SCHEMBL8713241 | 0.84 | PPARG (0.43) | PPARAPPARDHTR2AHTR2CHTR2B | |
| SCHEMBL8713237 | 0.84 | PPARG (0.43) | PPARAPPARDHTR2AHTR2CHTR2B | |
| SCHEMBL8714034 | 0.78 | ACHE (0.44) | MAPTLMNAPPARAPPARDPNMT | |
| SCHEMBL8714037 | 0.78 | ACHE (0.44) | MAPTLMNAPPARAPPARDPNMT | |
| SCHEMBL7153058 | 0.76 | ADRB2 (0.48) | SMN1; SMN2MAPTLMNAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |