Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714037 | 1.00 | ACHE (0.44) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8718425 | 0.86 | ALOX15 (0.52) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8718428 | 0.86 | ALOX15 (0.52) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8713237 | 0.85 | PPARG (0.43) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8713241 | 0.85 | PPARG (0.43) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8714129 | 0.83 | LDHA (0.48) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8714130 | 0.83 | LDHA (0.48) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8713251 | 0.78 | SMN1; SMN2 (0.47) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8713254 | 0.78 | SMN1; SMN2 (0.47) | ACHEPPARGPPARDPPARAALOX15 | |
| SCHEMBL8715437 | 0.74 | SIGMAR1 (0.51) | LDHALMNAMEN1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |