Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714129 | 1.00 | LDHA (0.48) | LDHAADRB2ACHESIGMAR1ALDH1A1 | |
| SCHEMBL8715434 | 0.90 | SIGMAR1 (0.51) | LDHAADRB2SIGMAR1ALDH1A1LMNA | |
| SCHEMBL8715437 | 0.90 | SIGMAR1 (0.51) | LDHAADRB2SIGMAR1ALDH1A1LMNA | |
| SCHEMBL8713241 | 0.87 | PPARG (0.43) | LDHAADRB2ACHEALOX15ALOX12 | |
| SCHEMBL8713237 | 0.87 | PPARG (0.43) | LDHAADRB2ACHEALOX15ALOX12 | |
| SCHEMBL8713857 | 0.85 | ALOX15 (0.53) | LDHAADRB2SIGMAR1ALDH1A1LMNA | |
| SCHEMBL8713854 | 0.85 | ALOX15 (0.53) | LDHAADRB2SIGMAR1ALDH1A1LMNA | |
| SCHEMBL8713254 | 0.84 | SMN1; SMN2 (0.47) | LDHAACHEALDH1A1LMNAKDM4E | |
| SCHEMBL8713251 | 0.84 | SMN1; SMN2 (0.47) | LDHAACHEALDH1A1LMNAKDM4E | |
| SCHEMBL8714034 | 0.83 | ACHE (0.44) | LDHAACHELMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |