Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717166 | 0.87 | LMNA (0.59) | KMT2ARAB9ALMNAHDAC1HDAC6 | |
| SCHEMBL8713771 | 0.86 | ADRB2 (0.45) | KIF11KMT2ARAB9AALDH1A1POLB | |
| SCHEMBL8713668 | 0.83 | LMNA (0.46) | KIF11KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8719238 | 0.83 | TPH1 (0.39) | KIF11RAB9ALMNAHDAC1ALDH1A1 | |
| SCHEMBL8714023 | 0.82 | TRPA1 (0.46) | KIF11LMNACYP1A2CYP3A4RECQL | |
| SCHEMBL8719185 | 0.82 | KIF11 (0.43) | KIF11MMP8PTPN1ALDH1A1CYP1A2 | |
| SCHEMBL8713320 | 0.80 | ESR1 (0.38) | KIF11LMNAALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL8716608 | 0.80 | KIF11 (0.44) | KIF11KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8714231 | 0.80 | ESR1 (0.53) | KIF11ALDH1A1CYP3A4 | |
| SCHEMBL8713802 | 0.80 | KIF11 (0.44) | KIF11KMT2ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |