Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713274 | 0.90 | RAB9A (0.50) | LMNARAB9AEPHX2NR1H4PPARG | |
| SCHEMBL8713301 | 0.87 | KIF11 (0.50) | LMNARAB9AEPHX2HDAC6HDAC1 | |
| SCHEMBL8719238 | 0.85 | TPH1 (0.39) | LMNARAB9AEPHX2NR1H4HDAC1 | |
| SCHEMBL8719185 | 0.84 | KIF11 (0.43) | EPHX2NR1H4RECQLCYP1A2CYP2C19 | |
| SCHEMBL8713668 | 0.83 | LMNA (0.46) | LMNAEPHX2NR1H4PPARGRECQL | |
| SCHEMBL8714023 | 0.82 | TRPA1 (0.46) | LMNAKDM4ERECQLCYP1A2CYP2C19 | |
| SCHEMBL8715390 | 0.80 | KIF11 (0.46) | EPHX2NR1H4HDAC6HDAC1RECQL | |
| SCHEMBL8714231 | 0.77 | ESR1 (0.53) | — | |
| SCHEMBL8713320 | 0.77 | ESR1 (0.38) | LMNACYP1A2CYP2C19 | |
| SCHEMBL8716608 | 0.77 | KIF11 (0.44) | MEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |