Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713637 | 1.00 | HSD11B1 (0.36) | HSD11B1HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL8718507 | 0.86 | PNMT (0.46) | HTR2AHTR2CHTR2BACP3 | |
| SCHEMBL8718504 | 0.86 | PNMT (0.46) | HTR2AHTR2CHTR2BACP3 | |
| SCHEMBL8716354 | 0.86 | GRIN2B (0.44) | HSD11B1HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL8716351 | 0.86 | GRIN2B (0.44) | HSD11B1HTR2AHTR2CHTR2BADRA2A | |
| SCHEMBL8718436 | 0.85 | ADRA2C (0.49) | HTR2AADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8718438 | 0.85 | ADRA2C (0.49) | HTR2AADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL8715306 | 0.84 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL8715309 | 0.84 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL8716593 | 0.83 | PPARG (0.44) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |