Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456055 | 0.67 | MAOA (0.49) | HSD17B10CA1CA2 | |
| SCHEMBL8551482 | 0.66 | PTGS2 (0.46) | PTGS1PTGS2XDHGFER | |
| SCHEMBL4173369 | 0.65 | PTGS1 (0.60) | PTGS1PTGS2NPC1RAB9AGFER | |
| SCHEMBL8551424 | 0.64 | PTGS1 (0.65) | PTGS1PTGS2XDHGFERCA12 | |
| SCHEMBL1613646 | 0.64 | XDH (0.71) | PTGS1PTGS2XDHNPC1RAB9A | |
| SCHEMBL10773308 | 0.63 | KMT2A (0.62) | PTGS1PTGS2XDHHSD17B10NPC1 | |
| SCHEMBL13601056 | 0.61 | KMT2A (0.69) | — | |
| SCHEMBL40525 | 0.61 | ALDH1A1 (0.69) | HSD17B10NPC1RAB9ACA12CA1 | |
| Benzene SCHEMBL28074647 | 0.61 | ALDH1A1 (0.69) | HSD17B10NPC1RAB9ACA12CA1 | |
| SCHEMBL28166896 | 0.61 | ALDH1A1 (0.69) | HSD17B10NPC1RAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10007658-A | — | — | None | — | — | JP | disclosed |
| JP-H107658-A | DERIVATIVE OF SULFONYL UREIDOPYRAZOLE | SUMITOMO PHARMACEUT CO LTD | 1998-01-13 | — | — | JP | disclosed |