Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718123 | 0.91 | TAOK1 (0.51) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL8714612 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL8718454 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL8714949 | 0.78 | KMT2A (0.54) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL8717614 | 0.78 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL8713941 | 0.77 | POLB (0.41) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL8715310 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8718492 | 0.74 | MAPT (0.42) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL8715140 | 0.72 | HDAC3 (0.38) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL8716872 | 0.72 | POLB (0.45) | MAPTALDH1A1L3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |