Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717614 | 0.83 | KMT2A (0.41) | POLBLMNAALDH1A1MAPTHPGD | |
| SCHEMBL8713941 | 0.82 | POLB (0.41) | POLBLMNAALDH1A1HPGD | |
| SCHEMBL8715140 | 0.81 | HDAC3 (0.38) | POLBLMNAALDH1A1KDM4EHDAC3 | |
| SCHEMBL8718454 | 0.78 | ALDH1A1 (0.48) | LMNAALDH1A1MAPTTSHRL3MBTL1 | |
| SCHEMBL8715310 | 0.78 | ALDH1A1 (0.46) | POLBALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8716877 | 0.77 | POLB (0.45) | POLBLMNATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8718492 | 0.75 | MAPT (0.42) | LMNAALDH1A1MAPTKDM4EHDAC3 | |
| SCHEMBL8717599 | 0.74 | MTNR1A (0.35) | POLBALDH1A1MAPTKDM4EHDAC3 | |
| SCHEMBL8714612 | 0.74 | ALDH1A1 (0.51) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL8713402 | 0.72 | ALDH1A1 (0.36) | POLBALDH1A1MAPTKDM4EHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |