Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713941 | 0.89 | POLB (0.41) | TP53POLBLMNAALDH1A1GAA | |
| SCHEMBL8718454 | 0.82 | ALDH1A1 (0.48) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8716872 | 0.81 | POLB (0.45) | HDAC3HDAC1HDAC7HDAC2HDAC10 | |
| SCHEMBL8717614 | 0.78 | KMT2A (0.41) | TP53POLBLMNAALDH1A1GAA | |
| SCHEMBL8715144 | 0.77 | CFD (0.39) | CFDTP53LMNA | |
| SCHEMBL8715310 | 0.76 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL8718492 | 0.74 | MAPT (0.42) | HDAC3HDAC1HDAC7HDAC2HDAC10 | |
| SCHEMBL8717599 | 0.73 | MTNR1A (0.35) | HDAC3HDAC1HDAC7HDAC2HDAC10 | |
| SCHEMBL8714612 | 0.72 | ALDH1A1 (0.51) | TP53POLBLMNAKDM4EALDH1A1 | |
| SCHEMBL8718123 | 0.72 | TAOK1 (0.51) | POLBKDM4EALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |