Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713244 | 0.86 | MEN1 (0.38) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL8718432 | 0.84 | LMNA (0.40) | LMNAMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8714131 | 0.84 | HTT (0.45) | LMNAMEN1KMT2AHTTSTAT3 | |
| SCHEMBL8713256 | 0.81 | SMN1; SMN2 (0.45) | LMNAMAPTHTTNPSR1KDM4E | |
| SCHEMBL8715439 | 0.76 | HTT (0.44) | LMNAMEN1KMT2AHTTSTAT3 | |
| SCHEMBL8713922 | 0.74 | LMNA (0.49) | LMNAMEN1KMT2AHTTRECQL | |
| SCHEMBL8714103 | 0.71 | EPHX2 (0.41) | LMNASTAT3CYP19A1CA2KDM4E | |
| SCHEMBL8717242 | 0.71 | ESR1 (0.46) | LMNANPSR1STAT3CYP19A1CA2 | |
| SCHEMBL8719246 | 0.70 | ATM (0.40) | KMT2AMAPK1HTTSTAT3CYP19A1 | |
| SCHEMBL8712989 | 0.70 | MMP1 (0.43) | LMNAKMT2ASTAT3CYP19A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |