Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 3/20 | 0.40 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714131 | 0.92 | HTT (0.45) | HTTSMN1; SMN2SIGMAR1KIF11ADRB2 | |
| SCHEMBL8713860 | 0.81 | HTT (0.47) | HTTSMN1; SMN2SIGMAR1KIF11ADRB2 | |
| SCHEMBL8713256 | 0.80 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8713244 | 0.80 | MEN1 (0.38) | HTTSMN1; SMN2KIF11MEN1KMT2A | |
| SCHEMBL8714039 | 0.76 | LMNA (0.39) | HTTSMN1; SMN2SIGMAR1MEN1KMT2A | |
| SCHEMBL8718953 | 0.73 | STAT3 (0.41) | HTTSMN1; SMN2SIGMAR1ADRB2MEN1 | |
| SCHEMBL8716946 | 0.73 | ADRB2 (0.41) | HTTSMN1; SMN2ADRB2LDHASTAT3 | |
| SCHEMBL8433303 | 0.72 | MEN1 (0.39) | HTTSMN1; SMN2KIF11MEN1KMT2A | |
| SCHEMBL8433905 | 0.72 | MEN1 (0.39) | HTTSMN1; SMN2KIF11MEN1KMT2A | |
| SCHEMBL8715550 | 0.72 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2STAT3CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |