Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718953 | 0.89 | STAT3 (0.41) | ATMKMT2AADRB2STAT3SMN1; SMN2 | |
| SCHEMBL8713152 | 0.89 | RAB9A (0.39) | ATMKMT2ASTAT3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8713354 | 0.87 | ALOX15 (0.40) | ATMKMT2AADRB2STAT3SMN1; SMN2 | |
| SCHEMBL8716671 | 0.87 | ADRB2 (0.40) | ATMKMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL8720032 | 0.87 | KDM4E (0.40) | ATMKMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL8713860 | 0.83 | HTT (0.47) | ATMKMT2AADRB2STAT3SMN1; SMN2 | |
| SCHEMBL8718108 | 0.82 | ABCB1 (0.46) | ATMKMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL8719259 | 0.82 | NR3C1 (0.39) | KMT2ASMN1; SMN2ALDH1A1NR3C1NR3C2 | |
| SCHEMBL8718432 | 0.81 | LMNA (0.40) | ATMKMT2ASTAT3SMN1; SMN2CYP19A1 | |
| SCHEMBL8713922 | 0.81 | LMNA (0.49) | ATMKMT2ASTAT3ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |