Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717242 | 0.90 | ESR1 (0.46) | STAT3LMNACYP19A1CA2ALDH1A1 | |
| SCHEMBL8712989 | 0.89 | MMP1 (0.43) | STAT3LMNACYP19A1SMN1; SMN2CTSD | |
| SCHEMBL8713922 | 0.89 | LMNA (0.49) | STAT3LMNACYP19A1CA2ALDH1A1 | |
| SCHEMBL8713860 | 0.89 | HTT (0.47) | STAT3LMNACYP19A1SMN1; SMN2CA2 | |
| SCHEMBL8716946 | 0.87 | ADRB2 (0.41) | STAT3LMNACYP19A1SMN1; SMN2POLB | |
| SCHEMBL8718432 | 0.84 | LMNA (0.40) | STAT3LMNACYP19A1SMN1; SMN2CTSD | |
| SCHEMBL8433303 | 0.81 | MEN1 (0.39) | STAT3LMNACYP19A1SMN1; SMN2CTSD | |
| SCHEMBL8433905 | 0.81 | MEN1 (0.39) | STAT3LMNACYP19A1SMN1; SMN2CTSD | |
| SCHEMBL8715550 | 0.81 | SMN1; SMN2 (0.47) | STAT3LMNACYP19A1SMN1; SMN2CTSD | |
| SCHEMBL8716671 | 0.81 | ADRB2 (0.40) | STAT3LMNACYP19A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |